Randy Bruno Lab at Columbia University

The goal of the Bruno Lab's research is to define the underlying neural pathways and circuit elements that  contribute to sensory perception: how information from the outside world is relayed to the neocortex, and how subsequent processing among cortical layers and thalamic nuclei contribute to perception, learning, remembering, and reasoning.

Our experiments combine behavior with intracellular physiology, array recordings, two-photon microscopy, optogenetics, and computational modeling. We focus on the whisker-barrel system, which is one of the main means by which rodents explore their environments.